Gates Foundation Supports Ebola ça Suffit Ring Vaccination Phase III Trial
The Gates Foundation helped fund the Ebola ça Suffit ring vaccination trial in Guinea — the Phase III study that proved the rVSV-ZEBOV vaccine was effective. The trial used a novel ring methodology: every contact and contact-of-contact of a confirmed Ebola case was randomly assigned to immediate or 21-day delayed vaccination. Interim results published in The Lancet in 2016 showed 100 percent vaccine efficacy in the immediate arm with no Ebola cases recorded. The findings provided the scientific foundation for deploying the vaccine — later branded Ervebo — in subsequent DRC outbreaks.
Source: https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(16)32621-6/fulltext
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