Gates Foundation Funds Aeras Inhaled Tuberculosis Vaccine Delivery for Needle-Free Lung Immunity
The Gates Foundation, through its long-term funding relationship with the Aeras Global TB Vaccine Foundation, supported research into inhaled tuberculosis vaccine delivery systems designed to induce mucosal and lung immunity directly at the site of TB infection. Conventional injectable TB vaccines do not produce the lung-resident T cell responses that researchers believe are necessary to prevent pulmonary disease. Aeras's inhaled delivery programme explored adenoviral vector and lipid-nanoparticle formats that could deliver antigens via aerosol or dry-powder inhalation without injection.
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Gates Foundation Grand Challenges Grant to Johns Hopkins for Malaria Mosquito Kill-Switch Pathogen
Related Accomplishments
January 2026
Gates-backed World Mosquito Program reaches 16 million people protected from dengue via Wolbachia method
The World Mosquito Program — backed in part by the Gates Foundation — announced in January 2026 that its Wolbachia-infected mosquito releases had reached over 16.1 million people across multiple countries, including Colombia, Indonesia, Brazil, Sri Lanka, Fiji, Vanuatu, and Vietnam. Wolbachia-carrying Aedes aegypti mosquitoes — which block dengue, Zika, chikungunya, and yellow fever transmission — had established self-sustaining populations in treated cities without requiring ongoing releases. Gold-standard randomised trials in Indonesia showed a 77% reduction in dengue incidence. The program represented one of the largest and most cost-effective vector control deployments in history.
December 2025
Gates Foundation Pledges $100 Million to Global Financing Facility for Women's and Children's Health 2026–2030
On December 6, 2025, at the Universal Health Coverage High-Level Forum in Tokyo, the Gates Foundation pledged $100 million to the World Bank-hosted Global Financing Facility's 2026–2030 strategy for ending preventable deaths among women, children, and adolescents in LMICs. The pledge brings the foundation's total GFF commitment past $500 million since 2015. The GFF provides catalytic grant financing and technical assistance to strengthen LMIC health systems and expand quality access to health and nutrition services for the world's most vulnerable populations.
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